HNF-6/ONECUT1 Antibody

Images

 
Western Blot: HNF-6/ONECUT1 Antibody [NBP2-27079] - Analysis ofHNF6 inhuman pancreas in the 1) absence and 2) presence of immunizing peptide, and 3) rat pancreasusing this antibody. Goat anti-rabbit Ig HRP secondary ...read more
Immunohistochemistry-Paraffin: HNF-6/ONECUT1 Antibody [NBP2-27079] - Analysis of HNF6 in formalin-fixed, paraffin-embedded human liver tissue using an isotype control (top) and this antibody (bottom) at 5 ug/ml.

Product Details

Summary
Reactivity Hu, Ca, Pm, Rt, Bv, Pm, PmSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

HNF-6/ONECUT1 Antibody Summary

Immunogen
A portion of amino acids 420-465 of human HNF6 was used as the immunogen.
Predicted Species
Rat (100%), Monkey (100%), Bovine (94%), Chimpanzee (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ONECUT1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5ug/ml
  • Western Blot 3-5ug/ml~

Reactivity Notes

The amino acid sequence used as immunogen is 88% homologous in Mouse and Opossum, and 82% homologous in Zebrafish.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.2 ml PBS and 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for HNF-6/ONECUT1 Antibody

  • HNF6
  • HNF-6
  • HNF-6A
  • HNF6Ahepatocyte nuclear factor 6, alpha
  • HNF6hepatocyte nuclear factor 6
  • HNF-6One cut domain family member 1
  • OC-1
  • one cut homeobox 1one cut domain, family member 1
  • ONECUT1

Background

Hepatocyte nuclear factor 6 is a CUT homeobox family protein which is a transcription factor and contains a CUT DNA-binding domain and a homeobox DNA-binding domain. It is an upstream regulator of several genes involved in the pathogenesis of maturity-onset diabetes of the young. HNF6 is a ligand of the FOXM1 transcription factor network. HNF6, along with HNF4, controls gene expression in the liver. The expression levels of HNF6 and HNF4 rise steadily during development and that up- or down regulation of HNF6 and HNF4 expression generate premature or delayed expression of the g6pc gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ONECUT1
Uniprot