Recombinant Human HMGB1/HMG-1 Protein

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Recombinant Human HMGB1/HMG-1 Protein [H00003146-P01] - 12.5% SDS-PAGE Stained with Coomassie Blue.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, PA, AP

Order Details

Recombinant Human HMGB1/HMG-1 Protein Summary

Description
A recombinant protein with GST tag at N-terminal corresponding to the amino acids 1-215 of Human HMGB1 full-length ORF

Source: Wheat Germ (in vitro)

Amino Acid Sequence:MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE

Details of Functionality
This protein is not active and should not be used for experiments requiring activity.
Source
Wheat germ
Protein/Peptide Type
Recombinant Protein
Gene
HMGB1
Purity
>80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

Application Notes
This protein has not been tested for any functionality. Product may contain endotoxins and is not suitable for use with live cells.
Theoretical MW
49.39 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publications using H00003146-P01.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Purity
>80% by SDS-PAGE and Coomassie blue staining

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Recombinant Human HMGB1/HMG-1 Protein

  • Amphoterin
  • high mobility group box 1
  • High mobility group protein 1
  • high mobility group protein B1
  • high-mobility group (nonhistone chromosomal) protein 1
  • high-mobility group box 1
  • HMG1
  • HMG-1
  • HMG1DKFZp686A04236
  • HMG3
  • HMGB1
  • SBP-1
  • Sulfoglucuronyl carbohydrate binding protein

Background

HMGB1( AAH03378, 1 a.a. - 216 a.a.) recombinant protein with GST.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Publications for HMGB1/HMG-1 Recombinant Protein (H00003146-P01)(31)


Showing Publications 1 - 10 of 31. Show All 31 Publications.
Publications using H00003146-P01 Applications Species
Lee IC, Kim DY, Bae JS. Sulforaphane Reduces HMGB1-Mediated Septic Responses and Improves Survival Rate in Septic Mice. Am J Chin Med 2017 Aug 22 [PMID: 28830206]
Lee W, Ku SK, Bae JS. Zingerone reduces HMGB1-mediated septic responses and improves survival in septic mice. Toxicol Appl Pharmacol 2017 Jun 10 [PMID: 28610995]
Min G, Ku SK, Park MS et al. Anti-septic effects of pelargonidin on HMGB1-induced responses in vitro and in vivo. Arch Pharm Res 2016 Dec [PMID: 27778275]
Lee W, Ku SK, Park S et al. Inhibitory Effect of Three Diketopiperazines from Marine-Derived Bacteria on HMGB1-Induced Septic Responses in Vitro and in Vivo. Am J Chin Med 2016 Sep 15 [PMID: 27627916]
Fang F, Jiang D. IL-1 B/HMGB1 Signaling Promotes the Inflammatory Cytokines Release via TLR S ignaling in Human Intervertebral Disc C ells. Biosci Rep 2016 Aug 10 [PMID: 27512095]
Yang EJ, Lee W, Song KS, Bae JS. Ameliorative effect of a rarely occurring C-methylrotenoid on HMGB1-induced septic responses in vitro and in vivo. Biochem Pharmacol 2016 Apr 19 [PMID: 27106082]
Tuan NQ, Lee W, Oh J et al. Flavanones and Chromones from Salicornia herbacea Mitigate Septic Lethality via Restoring Vascular Barrier Integrity. J Agric Food Chem. 2015 Oct 31 [PMID: 26522440]
Kwak S, Ku SK, Kang H et al. Methylthiouracil, a new treatment option for sepsis. Vascul Pharmacol. 2015 Aug 01 [PMID: 26239884]
Lee W, Park EJ, Kwak S et al. PEGylated lysozymes with anti-septic effects in human endothelial cells and in mice. Biochem Biophys Res Commun. 2015 Mar 11 [PMID: 25769950]
Kwak S, Ku SK, Han MS, Bae JS. Vascular barrier protective effects of baicalin, baicalein and wogonin in vitro and in vivo. Toxicol Appl Pharmacol. 2014 Sep 15 [PMID: 25223693]
Show All 31 Publications.

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Bioinformatics

Gene Symbol HMGB1
Entrez