HMGB1/HMG-1 Products

Antibodies
HMGB1/HMG-1 Antibody (2F6)
HMGB1/HMG-1 Antibody (2F6)
H00003146-M08
Species: Hu, Ec
Applications: WB, ChIP, ELISA, ICC/IF, IHC, IHC-P, B/N, KD
Host: Mouse Monoclonal
Antibody Pairs
HMGB1/HMG-1 Antibody Pair
HMGB1/HMG-1 Antibody Pair
H00003146-AP44
Species: Hu
Applications: S-ELISA
Host: Monoclonal
ELISA Kits
Human HMGB1/HMG-1 ELISA Kit ( ...
Human HMGB1/HMG-1 ELISA Kit (Color...
NBP2-62766
Species: Hu
Applications: ELISA
Mouse HMGB1/HMG-1 ELISA Kit ( ...
Mouse HMGB1/HMG-1 ELISA Kit (Chemi...
NBP2-62782
Species: Mu
Applications: ELISA
Mouse HMGB1/HMG-1 ELISA Kit ( ...
Mouse HMGB1/HMG-1 ELISA Kit (Color...
NBP2-62767
Species: Mu
Applications: ELISA
Lysates
HMGB1/HMG-1 Overexpression Ly ...
HMGB1/HMG-1 Overexpression Lysate
NBL1-11614
Species: Hu
Applications: WB
Proteins
Recombinant Human HMGB1/HMG-1 ...
Recombinant Human HMGB1/HMG-1 GST ...
H00003146-P01
Species: Hu
Applications: WB, ELISA, Func, ICC/IF, PA, PAGE, S-ELISA, AP, ELISA(Comp)
Recombinant Human HMGB1/HMG-1 ...
Recombinant Human HMGB1/HMG-1 Protein
NBP2-34960
Species: Hu
Applications: Func, PAGE
Recombinant Mouse HMGB1/HMG-1 ...
Recombinant Mouse HMGB1/HMG-1 Protein
NBP1-42888
Species: Mu
Applications: ELISA, IA, Bioactivity

Description

HMGB1 and HMGB2 are part of the chromatin non-histone high mobility group proteins 1 and 2. HMGB1 and HMGB2 (containing multiple HMG-boxes) are conserved domains of 80 amino acids which mediate the DNA binding of many proteins. HMG box domains recognize DNA structure. Both HMGB1 and HMGB2 contain a N-terminal HMG box, a central HMG box, and an acidic carboxy terminus. The acidic tails of HMGB1 and HMGB2 contain multiple serine residues which match the phosphorylation consensus sites of casein kinase II, and phosphorylation of this domain appears to be important for proper functioning of these proteins. HMGB1 and HMGB2 have been shown to facilitate the binding of various sequence-specific transcription factors to their respective DNA binding sites. HMGB1 and HMGB2 may also serve as architectural factors that recognize and mediate DNA structural changes that accompany various events such as DNA repair, transcription, and replication.

Bioinformatics

Entrez Mouse
Rat
Human
Uniprot Human
Human
Human
Human
Human
Human
Mouse
Rat
Product By Gene ID 3146
Alternate Names
  • Amphoterin
  • high mobility group box 1
  • High mobility group protein 1
  • high mobility group protein B1
  • high-mobility group (nonhistone chromosomal) protein 1
  • high-mobility group box 1
  • HMG-1
  • HMG1DKFZp686A04236
  • HMG3
  • SBP-1
  • Sulfoglucuronyl carbohydrate binding protein

Research Areas for HMGB1/HMG-1

Find related products by research area and learn more about each of the different research areas below.

Cellular Markers
Chromatin Research
Histones and Modified Histones
Neuroscience
Transcription Factors and Regulators

Bioinformatics Tool for HMGB1/HMG-1

Discover related pathways, diseases and genes to HMGB1/HMG-1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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Related HMGB1/HMG-1 Blog Posts

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