HMGB1/HMG-1 Products

Antibodies
HMGB1/HMG-1 Antibody
HMGB1/HMG-1 Antibody
Species: Hu, Mu, Rt, Bv, Ca, Rb, Sh, Equine, Porcine
Applications: WB, Simple Western, ELISA, Flow, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
HMGB1/HMG-1 Antibody (115603) ...
HMGB1/HMG-1 Antibody (115603) [Unc...
MAB1690
Species: Hu
Applications: WB, Flow, ChIP, ICC
Host: Mouse Monoclonal
Antibody Pairs
HMGB1/HMG-1 Antibody Pair
HMGB1/HMG-1 Antibody Pair
H00003146-AP44
Species: Hu
Applications: S-ELISA
HMGB1/HMG-1 Antibody Pair
HMGB1/HMG-1 Antibody Pair
H00003146-PW1
Species: Hu
Applications: WB, IP
Lysates
HMGB1/HMG-1 Overexpression Ly ...
HMGB1/HMG-1 Overexpression Lysate ...
NBL1-11614
Applications: WB
Proteins
HMGB1/HMG-1 Recombinant Prote ...
HMGB1/HMG-1 Recombinant Protein
H00003146-P01
Species: Hu
Applications: WB, ELISA, PA
Human HMGB1/HMG-1 His (C-Term ...
Human HMGB1/HMG-1 His (C-Term) Pro...
NBP2-34960
Species: Hu
Applications: Func, PAGE
HMGB1/HMG-1 Peptide
HMGB1/HMG-1 Peptide
NB100-2322PEP
Species: Mu
RNAi
HMGB1/HMG-1 RNAi
HMGB1/HMG-1 RNAi
H00003146-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

HMGB1 and HMGB2 are part of the chromatin non-histone high mobility group proteins 1 and 2. HMGB1 and HMGB2 (containing multiple HMG-boxes) are conserved domains of 80 amino acids which mediate the DNA binding of many proteins. HMG box domains recognize DNA structure. Both HMGB1 and HMGB2 contain a N-terminal HMG box, a central HMG box, and an acidic carboxy terminus. The acidic tails of HMGB1 and HMGB2 contain multiple serine residues which match the phosphorylation consensus sites of casein kinase II, and phosphorylation of this domain appears to be important for proper functioning of these proteins. HMGB1 and HMGB2 have been shown to facilitate the binding of various sequence-specific transcription factors to their respective DNA binding sites. HMGB1 and HMGB2 may also serve as architectural factors that recognize and mediate DNA structural changes that accompany various events such as DNA repair, transcription, and replication.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Mouse
Rat
Product By Gene ID 3146
Alternate Names
  • HMG-1
  • Sulfoglucuronyl carbohydrate binding protein
  • High mobility group protein 1
  • high mobility group protein B1
  • high-mobility group (nonhistone chromosomal) protein 1
  • high mobility group box 1
  • SBP-1
  • HMG3
  • HMG1DKFZp686A04236
  • Amphoterin
  • high-mobility group box 1

Research Areas for HMGB1/HMG-1

Find related products by research area and learn more about each of the different research areas below.

Cellular Markers
Chromatin Research
Histones and Modified Histones
Neuroscience
Transcription Factors and Regulators

Bioinformatics Tool for HMGB1/HMG-1

Discover related pathways, diseases and genes to HMGB1/HMG-1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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