HLA DPA Antibody

Western Blot: HLA DPA Antibody [H00003113-D01P] - Analysis of HLA-DPA1 expression in human kidney.

Western Blot: HLA DPA Antibody [H00003113-D01P] - Analysis of HLA-DPA1 expression in transfected 293T cell line by HLA-DPA1 polyclonal antibody.Lane 1: HLA-DPA1 transfected lysate(29.30 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

HLA DPA Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: HLA-DPA1 (AAH09956.1, 1 a.a. - 260 a.a.) full-length human protein. MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFVQTHRPTGEFMFEFDEDEQFYVDLDKKETVWHLEEFGRAFSFEAQGGLANIAILNNNLNTLIQRSNHTQAANDPPEVTVFPKEPVELGQPNTLICHIDRFFPPVLNVTWLCNGEPVTEGVAESLFLPRTDYSFHKFHYLTFVPSAEDVYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLIIKSLRSGHDPRAQGPL
• Specificity: HLA-DPA1 - major histocompatibility complex, class II, DP alpha 1,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HLA-DPA1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against transfected lysate for WB. It has been used for ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for HLA DPA Antibody

• DP alpha 1 chain
• HLA class II histocompatibility antigen, DP alpha chain
• HLADP
• HLA-SB alpha chain
• major histocompatibility complex, class II, DP alpha 1
• MHC class II antigen
• MHC class II DP3-alpha
• MHC class II DPA1
• MHC class II HLA-DPA1 antigen
• Primed lymphocyte test-1

Background

HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HLA-DPA1
• Entrez:
  • 3113(Human)
• Uniprot:
  • AAH09956.1(Human)