HIST1H2AC Antibody

Western Blot: HIST1H2AC Antibody [NBP1-45619] - Analysis of Histone H2A expression with HeLa nuclear lysate.

Product Discontinued

HIST1H2AC Antibody Summary

• Description: This product is manufactured by Abcam and distributed by Novus Biologicals. (Abcam Catalog Number: ab18975)
• Immunogen: Synthetic peptide corresponding to the N-terminus of human histone H2A.
• Specificity: It does not cross-react with other histones.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HIST1H2AC
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1 ug/ml
• Application Notes: Detects a band of approximately 14 kDa (predicted molecular weight: 16 kDa).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 30% Glycerol, 0.5% BSA, 0.015% EDTA
• Preservative: 0.03% Proclin 300
• Concentration: 0.5 mg/ml
• Purity: Affinity purified

Alternate Names for HIST1H2AC Antibody

• dJ221C16.4
• H2A/l
• H2AFLmember L
• histone 1, H2ac
• histone cluster 1, H2ac
• histone H2A type 1-C
• Histone H2A/l
• histone H2AC
• MGC99519

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: HIST1H2AC
• Entrez:
  • 8334(Human)
  • 319164(Mouse)
  • 499676(Rat)
• Uniprot:
  • Q93077(Human)