HFE Antibody [mFluor Violet 450 SE]

• Reactivity: Mu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: mFluor Violet 450 SE

HFE Antibody [mFluor Violet 450 SE] Summary

• Immunogen: Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human HFE
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HFE
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for HFE Antibody [mFluor Violet 450 SE]

• dJ221C16.10.1
• hemochromatosis
• hereditary hemochromatosis protein HLA-H
• hereditary hemochromatosis protein
• HFE
• HFE1
• HH
• high Fe
• HLAH
• HLA-H
• HLA-HHFE1
• MGC103790
• MHC class I-like protein HFE
• MVCD7
• TFQTL2

Background

HFE is encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HFE