Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Antibody (738306) [Janelia Fluor® 669]

• Reactivity: Hu
• Applications: WB
• Clone: 738306
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 669

Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Antibody (738306) [Janelia Fluor® 669] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1
  Met59-Asn356
  Accession # Q7LGA3
• Specificity: Detects human Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 in ELISAs and Western blots.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: HS2ST1
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Antibody (738306) [Janelia Fluor® 669]

• 2OST
• 2-O-sulfotransferase
• EC 2.8.2
• EC 2.8.2.-
• FLJ11317
• heparan sulfate 2-O-sulfotransferase 1
• HS2ST
• HS2ST1
• KIAA0448dJ604K5.2
• MGC131986

Background

Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes heparan sulfate 2-O-sulfotransferase, a member of the heparan sulfate biosynthetic enzyme family. This family member transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HS2ST1