HDAC10 Antibody

Western Blot: HDAC10 Antibody [NBP2-03973] - analysis of HDAC-10 in HeLa cells using this antibody.

Product Discontinued

HDAC10 Antibody Summary

• Immunogen: Recombinant human HDAC-10.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HDAC10
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:250-1:1000

Reactivity Notes

Human

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.1 ml PBS
• Preservative: 0.02% Sodium Azide
• Purity: Protein G purified

Alternate Names for HDAC10 Antibody

• DKFZP761B039
• EC 3.5.1.48
• EC 3.5.1.62
• EC 3.5.1.98
• HD10
• HDAC10
• histone deacetylase 10
• MGC149722

Background

A novel class II histone deacetylase, HDAC10 is most similar to HDAC6. Both contain a unique, putative second catalytic domain not found in other HDACs. In HDAC10, however, this domain is not functional. Unlike HDAC6, which is normally a cytoplasmic deacetylase, HDAC10 resides in both the nucleus and cytoplasm. Data suggests that HDAC10 may play roles both in the nucleus, as a transcriptional modulator, and in the cytoplasm in an unidentified role. HDAC10 variants seem present in certain cell lines and tissues that are as of yet not characterized..

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HDAC10
• Uniprot:
  • NP_060191(Human)