HDAC10 Products

Antibodies
HDAC10 Antibody
HDAC10 Antibody
NB100-91801
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
HDAC10 Antibody
HDAC10 Antibody
NB600-223
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
HDAC10 Antibody
HDAC10 Antibody
NBP2-03973
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
HDAC10 Overexpression Lysate ...
HDAC10 Overexpression Lysate (Dena...
H00083933-T01
Species: Hu
Applications: WB
HDAC10 Overexpression Lysate ...
HDAC10 Overexpression Lysate (Native)
NBL1-11478
Applications: WB
Proteins
HDAC10 Recombinant Protein
HDAC10 Recombinant Protein
H00083933-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
HDAC10 RNAi
HDAC10 RNAi
H00083933-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (for p300/CBP-associated factor), p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated mammalian RPD3) and HDAC3, all of which are related to the yeast transcriptional regulator Rpd3p, have been identified as histone deacetylases.

Bioinformatics

Entrez Human
Human
Rat
Uniprot Human
Human
Human
Product By Gene ID 83933
Alternate Names
  • EC 3.5.1.98
  • MGC149722
  • DKFZp761B039
  • DKFZP761B039
  • HD10
  • histone deacetylase 10

Research Areas for HDAC10

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
Checkpoint signaling
Chromatin Research
Epigenetics
Histone Deacetylases
Transcription Factors and Regulators

PTMs for HDAC10

Learn more about PTMs related to HDAC10.

Acetylation
Deacetylation
Phosphorylation
Cleavage
Methylation

Bioinformatics Tool for HDAC10

Discover related pathways, diseases and genes to HDAC10. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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