HABP2 Antibody (1H4)

Immunoprecipitation: HABP2 Antibody (1H4) [H00003026-M01] - Analysis of HABP2 transfected lysate using anti-HABP2 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with HABP2 MaxPab rabbit polyclonal antibody.

Sandwich ELISA: HABP2 Antibody (1H4) [H00003026-M01] - Detection limit for recombinant GST tagged HABP2 is approximately 1ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA, IP, S-ELISA
• Clone: 1H4
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

HABP2 Antibody (1H4) Summary

• Immunogen: HABP2 (NP_004123, 105 a.a. ~ 204 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. GNKCQKVQNTCKDNPCGRGQCLITQSPPYYRCVCKHPYTGPSCSQVVPVCRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEIGSDDCYVGDGYSYRG
• Specificity: HABP2 (1H4)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: HABP2
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunoprecipitation
  • Sandwich ELISA
  • Western Blot
• Application Notes: It has been used for ELISA. Antibody reactivity against recombinant protein on ELISA. GST alone used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for HABP2 Antibody (1H4)

• EC 3.4.21
• EC 3.4.21.-
• EC 3.4.21.4
• EC 3.4.21.92
• Factor seven-activating protease
• Factor VII-activating protease
• FSAPfactor VII activating protein
• HABP
• Hepatocyte growth factor activator-like protein
• HGFALhyaluronic acid binding protein 2
• hyaluronan binding protein 2
• hyaluronan-binding protein 2
• PHBPplasma hyaluronan binding protein
• Plasma hyaluronan-binding protein

Background

The protein encoded by this gene is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. The encoded protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not prothrombin, plasminogen, or the gamma chain of fibrinogen.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for HABP2 Antibody (H00003026-M01)(3)

Publications using H00003026-M01

• Altmae S, Kallak TK, Friden B, Stavreus-Evers A. Variation in Hyaluronan-Binding Protein 2 (HABP2) Promoter Region is Associated With Unexplained Female Infertility. Reprod Sci. 2010-11-22 [PMID: 21098215]
• Mambetsariev N, Mirzapoiazova T, Mambetsariev B et al. Hyaluronic Acid binding protein 2 is a novel regulator of vascular integrity . Arterioscler Thromb Vasc Biol;30(3):483-90. 2010-03-01 [PMID: 20042707]
• Shimoda H, Nakamura S, Hitoe S et al. Anti-Adipogenic Polyphenols of Water Shield Suppress TNF-?-Induced Cell Damage and Enhance Expression of HAS2 and HAPB2 in Adiponectin-Treated Dermal Fibroblasts. Nat Prod Chem Res 2014-08-20

Bioinformatics

• Gene Symbol: HABP2
• Entrez:
  • 3026(Human)
• OMIM:
  • 603924(Human)
• Uniprot:
  • NP_004123(Human)