GSTZ1 Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: GSTZ1 Antibody [NBP1-83320] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.

Immunohistochemistry-Paraffin: GSTZ1 Antibody [NBP1-83320] - Staining of human skeletal muscle shows moderate cytoplasmic positivity in myocytes.

Immunohistochemistry-Paraffin: GSTZ1 Antibody [NBP1-83320] - Staining of human liver shows strong cytoplasmic and nuclear positivity in hepatocytes.

Immunohistochemistry-Paraffin: GSTZ1 Antibody [NBP1-83320] - Staining of human kidney shows moderate cytoplasmic positivity in cells in tubules and in glomeruli.

Immunohistochemistry-Paraffin: GSTZ1 Antibody [NBP1-83320] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.

Immunohistochemistry-Paraffin: GSTZ1 Antibody [NBP1-83320] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts and leydig cells.

Analysis in human liver tissue.

• Reactivity: Hu
• Applications: WB, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

GSTZ1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit GSTZ1 Antibody - BSA Free (NBP1-83320) is a polyclonal antibody validated for use in IHC, WB and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: NLSVLKQVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDLTPYPTISSINKRLLVLEAFQVSHPCRQPDTPTELRA
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GSTZ1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  GSTZ1 Protein (NBP1-83320PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (81%), Rat (83%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for GSTZ1 Antibody - BSA Free

• EC 2.5.1.18
• EC 5.2.1.2
• glutathione S-alkyltransferase
• glutathione S-aralkyltransferase
• Glutathione S-transferase zeta 1
• glutathione transferase zeta 1
• GSTZ1-1maleylacetoacetate isomerase
• MAAIglutathione S-aryltransferase
• MAI
• maleylacetone isomerase
• MGC2029
• S-(hydroxyalkyl)glutathione lyase

Background

GSTZ1 is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GSTZ1