GSTZ1 Products

Description

GSTZ1 is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms.

Bioinformatics

Entrez	2954 Human
Uniprot	O43708 Human NP_665877 Human NP_665877.1 Human AAH01453 Human AAC33591 Human
Product By Gene ID	2954
Alternate Names	EC 5.2.1.2 glutathione S-alkyltransferase EC 2.5.1.18 MGC2029 S-(hydroxyalkyl)glutathione lyase Glutathione S-transferase zeta 1 maleylacetone isomerase MAI GSTZ1-1maleylacetoacetate isomerase MAAIglutathione S-aryltransferase glutathione S-aralkyltransferase glutathione transferase zeta 1

Diseases related to GSTZ1

Discover more about diseases related to GSTZ1.

Malignant Neoplasms
Acidosis
Acidosis, Lactic
Neoplasms
Malignant Neoplasm Of Breast
Mammary Neoplasms
Dysequilibrium Syndrome
Malignant Neoplasm Of Lung
Parkinson Disease
Lung Neoplasms
Malignant Neoplasm Of Urinary Bladder
Hepatotoxicity
Tyrosinemias
Leukopenia
Tyrosinemia, Type I
Bladder Neoplasm
Metabolic Diseases
Cholangiocarcinoma
Disease Of Adrenal Medulla
Malnutrition

Pathways for GSTZ1

View related products by pathway and learn more about each of the pathways below.

Dna Repair
Excretion
Pathogenesis
Dna Methylation
Conjugation
Localization
Liver Development
Methylation
Dna Hypermethylation
Cellular Senescence
Aging
Senescence
Cell Death

PTMs for GSTZ1

Learn more about PTMs related to GSTZ1.

Reduction
Methylation
Decarboxylation

Bioinformatics Tool for GSTZ1

Discover related pathways, diseases and genes to GSTZ1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.