GPR103 Antibody - BSA Free

Immunohistochemistry-Paraffin: GPR103 Antibody [NLS1922] - Brain, Hypothalamus, PVN

Immunohistochemistry-Paraffin: GPR103 Antibody [NLS1922] - Analysis of anti-QRFPR / GPR103 antibody with human brain, neurons and glia. at 10 ug/ ml.

Immunohistochemistry-Paraffin: GPR103 Antibody [NLS1922] - Brain, Accessory Nucleus

• Reactivity: Hu, Pm, Pm
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

GPR103 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 20 amino acid peptide from the C-terminal cytoplasmic domain of human GPR103.
• Epitope: C-Terminus cytoplasmic domain
• Localization: Cell Membrane
• Specificity: Human GPR103. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Monkey (95%), Primate (95%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: QRFPR
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 ug/ml
• Application Notes: .

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (95%), Gibbon (95%), Marmoset (95%), Canine (85%), Equine (80%), Rabbit (80%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for GPR103 Antibody - BSA Free

• AQ27
• G protein-coupled receptor 103
• GPR103
• G-protein coupled receptor 103
• MGC149217
• Orexigenic neuropeptide QRFP receptor
• pyroglutamylated RFamide peptide receptor
• QRFP receptor
• QRFPR
• SP9155

Background

The G protein-coupled receptor GPR103 is an Orphan-U GPCR with an unknown ligand. ESTs have been isolated from human B-cell/lung/testis, brain, breast, eye, head/neck, kidney, placenta, and prostate libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for GPR103 Antibody (NLS1922)(5)

Publications using NLS1922

• Prevost G, Picot M, Le Solliec MA et al. The neuropeptide 26RFa in the human gut and pancreas: potential involvement in glucose homeostasis Cartilage 2019-06-01 [PMID: 31234144] (IF/IHC, Human)
• Gaëtan Prévost, Arnaud Arabo, Marie-Anne Le Solliec, Justine Bons, Marie Picot, Julie Maucotel, Hind Berrahmoune, Mouna El Mehdi, Saloua Cherifi, Alexandre Benani, Emmanuelle Nédélec, Moïse Coëffier, Jérôme Leprince, Anneli Nordqvist, Valéry Brunel, Pierre Déchelotte, Hervé Lefebvre, Youssef Anouar, Nicolas Chartrel Neuropeptide 26RFa (QRFP) is a key regulator of glucose homeostasis and its activity is markedly altered in obese/hyperglycemic mice. American journal of physiology. Endocrinology and metabolism 2020-02-18 [PMID: 31084498]
• Prevost G, Jeandel L, Arabo A et al. Hypothalamic Neuropeptide 26RFa Acts as an Incretin to Regulate Glucose Homeostasis. Diabetes 2015-08-01 [PMID: 25858563]
• Alonzeau J, Alexandre D, Jeandel L et al. The neuropeptide 26RFa is expressed in human prostate cancer and stimulates the neuroendocrine differentiation and the migration of androgeno-independent prostate cancer cells Eur J Cancer 2012-08-02 [PMID: 22863147] (IF/IHC, Human)
• Eckmann CR, Neunteufl A, Pfaffstetter L, Jantsch MF. The human but not the Xenopus RNA-editing enzyme ADAR1 has an atypical nuclear localization signal and displays the characteristics of a shuttling protein. Mol Biol Cell 2001-07-01 [PMID: 11451992]

Bioinformatics

• Gene Symbol: QRFPR
• Entrez:
  • 84109(Human)
• Uniprot:
  • Q96P65(Human)