GPD2 Antibody [DyLight 680]

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 680

GPD2 Antibody [DyLight 680] Summary

• Immunogen: Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human GPD2.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GPD2
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for GPD2 Antibody [DyLight 680]

• EC 1.1.5.3
• GDH2
• glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
• GPD2
• GPDH-M
• GPDM
• GPD-M
• mGDH
• mGPDH
• mitochondrial glycerophosphate dehydrogenase
• mitochondrial
• mtGPD

Background

Mitochondrial glycerophosphate dehydrogenase (EC 1.1.99.5), or GPD2, is located on the outer surface of the inner mitochondrial membrane and catalyzes the unidirectional conversion of glycerol-3-phosphate (G-3-P) to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD. Together with a cytosolic NAD-linked GPD (GPD1; MIM 138420), GPD2 forms the glycerol phosphate shuttle, which uses the interconversion of G-3-P and DHAP to transfer reducing equivalents into mitochondria, resulting in the reoxidation of NADH formed during glycolysis.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GPD2