Glycophorin A Antibody (BRIC 256)

Product Discontinued

Glycophorin A Antibody (BRIC 256) Summary

• Immunogen: Native, intact human erythrocytes
• Specificity: Specific for Glycophorin A, also known as CD235a. Glycophorin A is widely found on all erythroid cells and tissues. There are approx 500,000 GPA molecules per RBC. Rare individuals are deficient in GPA.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: GYPA
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:100-1:2000

Reactivity Notes

Reacts with Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: TBS (pH 7.2)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein G purified

Alternate Names for Glycophorin A Antibody (BRIC 256)

• CD235a antigen
• CD235a
• glycophorin A (includes MN blood group)
• glycophorin A (MNS blood group)
• Glycophorin A
• glycophorin Erik
• glycophorin MiI
• glycophorin MiIII
• glycophorin MiV
• glycophorin MiX
• glycophorin SAT
• glycophorin Sta type C
• glycophorin-A
• GPA
• GPErik
• GpMiIII
• GPSAT
• GYPA
• HGpMiIII
• HGpMiV
• HGpMiX
• HGpMiXI
• HGpSta(C)
• Mi.V glycoprotein (24 AA)
• MN sialoglycoprotein
• MNS
• PAS-2
• recombinant glycophorin A-B Miltenberger-DR

Background

Glycophorins A (GPA) and B (GPB) are single pass membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GYPA
• Entrez:
  • 2993(Human)
• Uniprot:
  • P02724()