Glutathione Peroxidase 7 Antibody

Western Blot: Glutathione Peroxidase 7 Antibody [NB100-41103] - Analysis of Glutathione Peroxidase 7 in Human Prostate lysate using this antibody at 0.3 ug/mL. With (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

Glutathione Peroxidase 7 Antibody Summary

• Description: Novus Biologicals Goat Glutathione Peroxidase 7 Antibody (NB100-41103) is a polyclonal antibody validated for use in WB and ELISA. Anti-Glutathione Peroxidase 7 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence CNQFGQQEPDSNK corresponding to internal region according to NP_056511.2.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: GPX7
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:32000
  • Western Blot 0.3 - 1 ug/mL
• Control:

  Glutathione Peroxidase 7 Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Glutathione Peroxidase 7 Antibody

• CL683
• EC 1.11.1
• FLJ14777
• glutathione peroxidase 6
• glutathione peroxidase 7
• GPX6EC 1.11.1.9
• GPx-7
• GSHPx-7
• non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase
• NPGPx

Background

Glutathione peroxidase 7 (GPX7) belongs to an enzyme family with peroxidase activity whose main biological role is to protect the organism from oxidative damage. The biochemical function of glutathione peroxidase is to reduce lipid hydroperoxides to their corresponding alcohols and to reduce free hydrogen peroxide to water. There are several isozymes encoded by different genes, which vary in celullar location and substrate specificity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Glutathione Peroxidase 7 Antibody (NB100-41103)(1)

Publication using NB100-41103

• Utomo A, Jiang X, Furuta S et al. Identification of a novel putative non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase (NPGPx) essential for alleviating oxidative stress generated from polyunsaturated fatty acids in breast cancer cells. J Biol Chem 2004-10-15 [PMID: 15294905]

Bioinformatics

• Gene Symbol: GPX7
• Entrez:
  • 2882(Human)
  • 67305(Mouse)
  • 298376(Rat)
• Uniprot:
  • NP_056511.2(Human)