Glutamate Receptor 6 Antibody (8A1F11) - BSA Free

Western Blot: Glutamate Receptor 6 Antibody (8A1F11) [NBP2-61788] - Analysis using GRIK2 mAb against human GRIK2 (AA: extra 45-226) recombinant protein. (Expected MW is 46.5 kDa)

Western Blot: Glutamate Receptor 6 Antibody (8A1F11) [NBP2-61788] - Analysis using GRIK2 mAb against HEK293 (1) and GRIK2 (AA: extra 45-226)-hIgGFc transfected HEK293 (2) cell lysate.

ELISA: Glutamate Receptor 6 Antibody (8A1F11) [NBP2-61788] - Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 8A1F11
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Glutamate Receptor 6 Antibody (8A1F11) - BSA Free Summary

• Description: Novus Biologicals Mouse Glutamate Receptor 6 Antibody (8A1F11) - BSA Free (NBP2-61788) is a monoclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Purified recombinant fragment of human Glutamate Receptor 6 (AA: extra 45-226) expressed in E. Coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: GRIK2
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:100-1:2000
• Theoretical MW: 102.5 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein G purified

Alternate Names for Glutamate Receptor 6 Antibody (8A1F11) - BSA Free

• EAA4
• GLR6
• GluK2
• GLUK6
• GluR6
• glutamate receptor 6
• glutamate receptor, ionotropic, kainate 2
• ionotropic kainate 2
• MGC74427
• MRT6

Background

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GRIK2