Glut2 Antibody

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Immunohistochemistry-Paraffin: Glut2 Antibody [NBP1-52560] - Analysis of anti-GLUT2 antibody with human liver at concentration 2.5 ug/ml.

Product Details

Summary
Reactivity Hu, Po, Bt, Eq, Mk, Pm, RbSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Glut2 Antibody Summary

Immunogen
Synthetic peptide C-RKEREEASSEQKVS from an internal region of human SLC2A2 / GLUT2 (NP_000331.1).
Specificity
Human SLC2A2 / GLUT2.
Predicted Species
Porcine (93%), Rabbit (93%), Primate (93%), Bat (93%), Monkey (93%), Equine (93%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
SLC2A2
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 2.5 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (93%), Panda (93%), Rat (86%), Sheep (86%), Elephant (86%), Canine (86%), Bovine (86%).

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
TBS (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Glut2 Antibody

  • GLUT2 Glucose transporter type 2, liver
  • Glut2
  • GLUT-2
  • SLC2A2
  • solute carrier family 2 (facilitated glucose transporter), member 2
  • solute carrier family 2, facilitated glucose transporter member 2

Background

Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. Seven types of glucose transport carrier proteins, designated as Glut 1 to 7, facilitate glucose transport across the cell membrane. Molecular cloning of glucose transporters have identified a family of closely related genes that encode at least 7 proteins exhibiting high degree of amino acid homology (45% to 65%), all in the molecular weight range of 40 to 60 kDa. Individual members of the Glut family have predicted secondary structure characteristic of 12 membrane spanning domains of other transport carriers. The majority of differences in sequence homology in Glut proteins occur at 4 hydrophilic domains that may play a role in distinct tissue specific pattern of expression and targeting. All Glut proteins are glycosylated at or near the C terminus and are present on either cell surface or in intracellular sites. Some transporters exhibit dynamic trafficking between intracellular storage sites and plasma membranes in response to various stimuli. In some tissues Glut proteins are asymmetrically distributed between apical and basolateral membranes as in blood brain barrier and blood testis barriers.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for Glut2 Antibody (NBP1-52560). (Showing 1 - 1 of 1 FAQ).

  1. Could you help this customer find a monoclonal antibody specific to rat's Glut2 protein to be used in IHC. I looked on our website and found one specific to Human's Glut2. Does this one cross react with Rat as well?
    • I have found the following antibody that would be suitable for you: NBP1-52560 I have included the peptide sequence below for the customer so that they can verify the homology with Rat. It is predicted and guaranteed to work in rat samples based on the sequence homology. If this antibody does not perform as expected you may receive a refund or replacement.

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SLC2A2
Entrez
Uniprot