Glut2 Antibody (199017) [Alexa Fluor™ Plus 555]

• Reactivity: Hu
• Clone: 199017
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 555

Glut2 Antibody (199017) [Alexa Fluor™ Plus 555] Summary

• Specificity: Recognizes human Glut2 expression on human Glut2‑transfected NS0 cells, but not on control transfectants. Was shown to detect Glut2 on the surface of the human intestinal cell line Caco2 (2) in flow cytometry and on fixed cells in immunocytochemistry tests. Based on flow cytometric tests on transfected cells, this antibody has no cross-reactivity with human Glut1 or human Glut3.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Glut2 Antibody (199017) [Alexa Fluor™ Plus 555]

• GLUT2 Glucose transporter type 2, liver
• Glut2
• GLUT-2
• SLC2A2
• solute carrier family 2 (facilitated glucose transporter), member 2
• solute carrier family 2, facilitated glucose transporter member 2

Background

Glut2 belongs to the facilitative glucose transporter protein family that comprises 13 members. It is an integral membrane protein with 12 transmembrane domains. Glut2 is expressed predominantly in liver, intestine, kidney, and pancreatic beta-cells. It is a low-affinity glucose transporter that has been suggested to function as a glucose sensor in pancreatic beta-cells and facilitate either glucose uptake or efflux from cells depending on the nutritional state (1).

1. Olson, A.L. and J.E. Pessin (1996) Annu. Rev. Nut. 16:235.
2. Mahraoui, L. et al. (1994) J. Biochem. 298:629.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.