GluR7/GRIK3 Antibody

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Western Blot: GluR7/GRIK3 Antibody [NBP1-20930] - Analysis in Rat Brain lysate (35ug protein in RIPA buffer) at 0.3ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity Mu, RtSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

GluR7/GRIK3 Antibody Summary

Immunogen
Peptide with sequence C-KIRQLPIDSDDSRP corresponding to internal region according to NP_000822.2.
Epitope
C terminus
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
GRIK3
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 0.3 - 1 ug/ml
  • Peptide ELISA Detection limit 1:64000
Application Notes
WB: Approx. 110 kDa band observed in mouse brain and rat brain lysates (calculated MW of 104 kDa band according to human NP_000822.2, and to rat NP_001106187.1). An additional band of unknown identity was also consistently observed at 39 kDa. This band was successfully blocked by incubation with the immunizing peptide.
Publications
Read Publication using NBP1-20930.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Human, Canine, Bovine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for GluR7/GRIK3 Antibody

  • EAA5
  • Excitatory amino acid receptor 5
  • GLR7
  • GluK3
  • GluR7
  • gluR-7
  • GluR7a
  • GLUR7dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7))
  • Glutamate receptor 7
  • glutamate receptor, ionotropic kainate 3
  • glutamate receptor, ionotropic, kainate 3
  • GRIK3

Background

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for GluR7/GRIK3 Antibody (NBP1-20930)(1)

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Video Protocols

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Bioinformatics

Gene Symbol GRIK3
Entrez
Uniprot