GluR7/GRIK3 Antibody (4H1)

Product Discontinued

GluR7/GRIK3 Antibody (4H1) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: GRIK3 (NP_000822, 151 a.a. ~ 250 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. NLYPDYASLSHAILDLVQYLKWRSATVVYDDSTGLIRLQELIMAPSRYNIRLKIRQLPIDSDDSRPLLKEMKRGREFRIIFDCSHTMAAQILKQAMAMGM
• Specificity: GRIK3 (4H1)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: GRIK3
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Antibody reactivity against recombinant protein on ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for GluR7/GRIK3 Antibody (4H1)

• EAA5
• Excitatory amino acid receptor 5
• GLR7
• GluK3
• GluR7
• gluR-7
• GluR7a
• GLUR7dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7))
• Glutamate receptor 7
• glutamate receptor, ionotropic kainate 3
• glutamate receptor, ionotropic, kainate 3
• GRIK3

Background

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GRIK3
• Entrez:
  • 2899(Human)
• OMIM:
  • 138243(Human)
• Uniprot:
  • NP_000822(Human)