GluR1 [p Ser831] Antibody

Product Discontinued

GluR1 [p Ser831] Antibody Summary

• Immunogen: Synthetic peptide corresponding to amino acids surrounding the phosphoSer381 of rat GluR1.
• Modification: p Ser831
• Specificity: Glutamate Receptor 1 [GluR1], phosphoSer831. The antibody recognizes a protein of 100 kDa corresponding to GluR1 phosphorylated at Ser831 in rat hippocampal homogenate.
• Predicted Species: Human (100%), Mouse (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GRIA1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Dot Blot 1:1000
  • Western Blot 1:1000
• Application Notes: Western Blot and dot Blots: The working dilution should be based on the tissue and the expected phosphorylation state.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Relevant Entrez Gene Numbers: NM_000827.2

Alternate Names for GluR1 [p Ser831] Antibody

• AMPA 1
• AMPA-selective glutamate receptor 1
• GluA1
• GLUH1
• GluR1
• gluR-1
• GLUR1gluR-A
• GLURA
• GluR-A
• gluR-K1
• glutamate receptor 1
• Glutamate receptor ionotropic, AMPA 1
• glutamate receptor, ionotropic, AMPA 1
• GRIA1
• HBGR1
• MGC133252

Background

Glutamate Receptor 1 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for Glutamate Receptor 1. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GRIA1
• Uniprot:
  • P42261(Human)