GluR1 Products

Description

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The GRIA1 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Each of the members (GRIA1-4) include flip and flop isoforms generated by alternative RNA splicing. The receptor subunits encoded by each isoform vary in their signal transduction properties. The isoform presented here is the flop isoform. In situ hybridization experiments showed that human GRIA1 mRNA is present in granule and pyramidal cells in the hippocampal formation.

Bioinformatics

Entrez	2890 Human 14799 Mouse 50592 Rat
Uniprot	P42261 Human P23818 Mouse P19490 Rat
Product By Gene ID	2890
Alternate Names	AMPA 1 AMPA-selective glutamate receptor 1 GluA1 GLUH1 GluR1 gluR-1 GLUR1gluR-A GLURA GluR-A gluR-K1 glutamate receptor 1 Glutamate receptor ionotropic, AMPA 1 glutamate receptor, ionotropic, AMPA 1 GRIA1 HBGR1 MGC133252

Research Areas for GluR1

Find related products by research area and learn more about each of the different research areas below.

Neuronal Cell Markers
Neuroscience
Neurotransmission