GLIS3 Antibody - BSA Free

Western Blot: GLIS3 Antibody [NBP2-16668] - A. 30 ug A431 whole cell lysate/extract 7.5 % SDS-PAGE GLIS3 antibody dilution: 1:1000.

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

GLIS3 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit GLIS3 Antibody - BSA Free (NBP2-16668) is a polyclonal antibody validated for use in WB. Anti-GLIS3 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human GLIS3. The exact sequence is proprietary.
• Localization: Nucleus
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GLIS3
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:3000
• Theoretical MW: 84 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (85%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for GLIS3 Antibody - BSA Free

• FLJ38999
• FLJ90578
• GLIS family zinc finger 3
• GLI-similar 3
• OK/KNS-cl.4
• zinc finger protein 515
• zinc finger protein GLIS3

Background

This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for GLIS3 Antibody (NBP2-16668)(1)

Publication using NBP2-16668

• Jayachandran A, Prithviraj P, Lo PH et al. Identifying and targeting determinants of melanoma cellular invasion. Oncotarget. 2016-07-05 [PMID: 27172792]

Bioinformatics

• Gene Symbol: GLIS3
• Uniprot:
  • Q8NEA6(Human)