GITR/TNFRSF18 Antibody (DTA-1) Summary
Mouse CD25+ CD4+ T cell line NP_683700
Protein G purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS containing 0.05% BSA.
0.05% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
Protein G purified
Alternate Names for GITR/TNFRSF18 Antibody (DTA-1)
- Activation-inducible TNFR family receptor
- AITRTNF receptor superfamily activation-inducible protein
- CD357 antigen
- GITRtumor necrosis factor receptor superfamily member 18
- Glucocorticoid-induced TNFR-related protein
- tumor necrosis factor receptor superfamily, member 18
GITR or TNFRSF18 is a 241 amino acid novel member of the tumor necrosis factor receptor superfamily and a receptor for TNFSF18. It has three extracytoplasmic cysteine-rich pseudorepeats, a small cytoplasmic tail and a DEATH domain. It is an essential regulator of immune responses to self tissues and pathogens and plays a key role in dominant immunological self-tolerance maintained by CD25 (+) CD4 (+) regulatory T cells. It is known to be involved in regulation of CD3-driven T-cell activation and programmed cell death and also in interactions between activated T-lymphocytes and endothelial cells. In mammalian cells it mediates NF-kappa-B activation via TRAF2 and modulates T lymphocyte survival in peripheral tissues. It is mostly expressed in lymph node, peripheral blood leukocytes and weakly expressed in spleen. GITR and its ligand are also known to be involved in atopic dermatitis.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
Customers Who Viewed This Item Also Viewed...
Species: Hu, Mu
Applications: Flow, IHC, ICC
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Applications: WB, ELISA, ICC/IF, S-ELISA
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Applications: WB, ICC/IF, IHC, IHC-P
Species: Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Cell Depl, InhibTFunc
Applications: Flow, Func, In vitro, In vivo, Flow-CS
Applications: WB, Flow, AgAct
Applications: WB, Flow, Func, IHC, IHC-Fr, IP
Species: Hu, Mu, Rt, Bv, Ca, Ch, Xp
Publications for GITR/TNFRSF18 Antibody (NBP2-26661) (0)
There are no publications for GITR/TNFRSF18 Antibody (NBP2-26661).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for GITR/TNFRSF18 Antibody (NBP2-26661) (0)
There are no reviews for GITR/TNFRSF18 Antibody (NBP2-26661).
By submitting a review earn points towards our Rewards Program.
- 250 points for product review
- 500 additional points for an image with your product review
- Double points (500) if you are the first to review this product
- Double points (1000) if you are the first to review this product with an image
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
FAQs for GITR/TNFRSF18 Antibody (NBP2-26661). (Showing 1 - 1 of 1 FAQ).
I was wondering if this antibody has been epitope mapped. If not, is the hybridoma available?
- Unfortunately, this product has not been epitope mapped, and we unfortunately do not have the hybridoma available for sale.
Other Available Formats
Additional GITR/TNFRSF18 Antibody (DTA-1) Products
Related Products by Gene
Bioinformatics Tool for GITR/TNFRSF18 Antibody (NBP2-26661)
Discover related pathways, diseases and genes to GITR/TNFRSF18 Antibody (NBP2-26661). Need help?
Read the Bioinformatics Tool Guide
for instructions on using this tool.
PTMs for GITR/TNFRSF18 Antibody (NBP2-26661)
Learn more about PTMs related to GITR/TNFRSF18 Antibody (NBP2-26661).
Research Areas for GITR/TNFRSF18 Antibody (NBP2-26661)
Find related products by research area.
Blogs on GITR/TNFRSF18