GFR alpha-4/GDNF R alpha-4/Persephin receptor Antibody [Unconjugated]

• Reactivity: Mu
• Applications: IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

GFR alpha-4/GDNF R alpha-4/Persephin receptor Antibody [Unconjugated] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse GFR alpha ‑4/GDNF R alpha ‑4
  Asn24-Thr237
  Accession # Q99JT2
• Specificity: Detects mouse GFR alpha ‑4/GDNF R alpha ‑4 in direct ELISAs and Western blots. In direct ELISAs, approximately 15% cross-reactivity with recombinant human GFR alpha -4 is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: GFRA4
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 5-15 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for GFR alpha-4/GDNF R alpha-4/Persephin receptor Antibody [Unconjugated]

• GDNF family receptor alpha 4
• GDNF family receptor alpha-4
• GDNF R alpha-4
• GDNF receptor alpha-4
• GDNFR-alpha-4
• GFR alpha4
• GFR alpha-4
• GFR receptor alpha 4
• GFRA4
• GFRa-4
• GFR-alpha-4
• Persephin receptor

Background

GFR alpha -4 is a GPI-linked cell surface protein that associates with the c-Ret transmembrane tyrosine kinase to form a functional receptor complex for the GDNF family ligand, persephin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for GFR alpha-4/GDNF R alpha-4/Persephin receptor Antibody (AF1677)(1)

Publication using AF1677

• Lindfors PH, Lindahl M, Rossi J, Saarma M, Airaksinen MS Ablation of persephin receptor glial cell line-derived neurotrophic factor family receptor alpha4 impairs thyroid calcitonin production in young mice. Endocrinology, 2006-02-23;147(5):2237-44. 2006-02-23 [PMID: 16497798] (IHC-Fr, Mouse)

Bioinformatics

• Gene Symbol: GFRA4
• Uniprot:
  • Q99JT2()