GFR alpha-4/GDNF R alpha-4/Persephin receptor Products

Antibodies
GFR alpha-4/GDNF R alpha-4/Pe ...
GFR alpha-4/GDNF R alpha-4/Perseph...
AF1677
Species: Mu
Applications: WB, IHC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
GFR alpha-4/GDNF R alpha-4/Pe ...
GFR alpha-4/GDNF R alpha-4/Perseph...
MAB1439
Species: Hu
Applications: WB
Host: Mouse Monoclonal
GFR alpha-4/GDNF R alpha-4/Pe ...
GFR alpha-4/GDNF R alpha-4/Perseph...
AF1439
Species: Hu
Applications: WB
Host: Goat Polyclonal
Lysates
GFR alpha-4/GDNF R alpha-4/Pe ...
GFR alpha-4/GDNF R alpha-4/Perseph...
NBP2-11268
Applications: WB
GFR alpha-4/GDNF R alpha-4/Pe ...
GFR alpha-4/GDNF R alpha-4/Perseph...
NBP2-06460
Applications: WB
GFR alpha-4/GDNF R alpha-4/Pe ...
GFR alpha-4/GDNF R alpha-4/Perseph...
NBL1-11054
Applications: WB
RNAi
GFR alpha-4/GDNF R alpha-4/Pe ...
GFR alpha-4/GDNF R alpha-4/Perseph...
H00064096-R06
Species: Hu
Applications: RNAi, RNAi SP
GFR alpha-4/GDNF R alpha-4/Pe ...
GFR alpha-4/GDNF R alpha-4/Perseph...
H00064096-R04
Species: Hu
Applications: RNAi, RNAi SP
GFR alpha-4/GDNF R alpha-4/Pe ...
GFR alpha-4/GDNF R alpha-4/Perseph...
H00064096-R05
Species: Hu
Applications: RNAi, RNAi SP

Description

Glial cell line-derived neurotrophic factor (GDNF) and the related neurotrophic factor neurturin (NTN) are potent survival factors for central and peripheral neurons. Receptors for these factors include GFRalpha-1 (previously designated GDNFR-alpha), GFRalpha-2 (also designated RETL2), GFRalpha-3 and GFRalpha-4 (also known as persephin receptor). The receptors do not contain transmembrane domains and are attached to the cell membrane by glycosylphosphoinositol linkage. Binding of GDNF or NTN to one of these receptors leads to the activation of the tyrosine kinase Ret. GFRalpha-4 mediates the activation and GDNF-induced autophosphorylation of the RET receptor. It is mainly expressed in the adult thyroid gland, but lower levels may also be detected in fetal adrenal and thyroid glands.

Bioinformatics

Uniprot Human
Human
Product By Gene ID 64096
Alternate Names
  • GFR-alpha-4
  • GFR receptor alpha 4
  • GDNFR-alpha-4
  • GDNF family receptor alpha-4
  • Persephin receptor
  • GDNF receptor alpha-4
  • GDNF family receptor alpha 4

Pathways for GFR alpha-4/GDNF R alpha-4/Persephin receptor

View related products by pathway and learn more about each of the pathways below.

Cell Development
Pathogenesis
Spermatogenesis
Secretion

PTMs for GFR alpha-4/GDNF R alpha-4/Persephin receptor

Learn more about PTMs related to GFR alpha-4/GDNF R alpha-4/Persephin receptor.

Phosphorylation
Glycosylation

Bioinformatics Tool for GFR alpha-4/GDNF R alpha-4/Persephin receptor

Discover related pathways, diseases and genes to GFR alpha-4/GDNF R alpha-4/Persephin receptor. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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