GCAT Antibody [Janelia Fluor® 635]

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Janelia Fluor 635

GCAT Antibody [Janelia Fluor® 635] Summary

• Immunogen: Produced in rabbits immunized with E. coli-derived Human GCAT fragment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GCAT
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for GCAT Antibody [Janelia Fluor® 635]

• 2-amino-3-ketobutyrate-CoA ligase
• AKB ligase
• Aminoacetone synthase
• EC 2.3.1
• EC 2.3.1.29
• Glycine acetyltransferase
• glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase)
• glycine C-acetyltransferase
• KBL2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
• MGC23053

Background

The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threoninedehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrateby L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reactionbetween 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a classII pyridoxal-phosphate-dependent aminotransferase. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GCAT