Gas6 Antibody (100127) [HRP]

• Reactivity: Hu
• Applications: WB
• Clone: 100127
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: HRP

Gas6 Antibody (100127) [HRP] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Gas6
  Asp118-Ala678
  Accession # NP_000811
• Specificity: Detects human Gas6 in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody shows approximately 5% cross‑reactivity with recombinant mouse Gas6.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: GAS6
• Purity: Protein A or G purified from ascites

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A or G purified from ascites

Alternate Names for Gas6 Antibody (100127) [HRP]

• AXLLG
• AXLLGAXL stimulatory factor
• AXSFAXL receptor tyrosine kinase ligand
• DKFZp666G247
• FLJ34709
• Gas6
• GAS-6
• growth arrest-specific 6
• growth arrest-specific protein 6

Background

Growth arrest specific proteins, including Gas1 and Gas6, are activated in quiescent cells. Gas1-induced growth arrest is mediated by p53, and Gas1 appears to be able to suppress tumor cell growth. Gas6, a ligand for the tyrosine kinase receptor Axl, was initially identified as a member of the vitamin K-dependent protein family and exhibits a high degree of amino acid sequence homology to protein S, a negative co-regulator in the coagulation pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GAS6