GABA-B R1 Antibody - BSA Free

Western Blot: GABA-B R1 Antibody [NB300-160] - Brain lysate with GABA-B R1 antibody at a dilution of 1:500.

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

GABA-B R1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit GABA-B R1 Antibody - BSA Free (NB300-160) is a polyclonal antibody validated for use in WB. Anti-GABA-B R1 Antibody: Cited in 3 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Synthetic peptide corresponding to residues 33-54 [PHLPRPHPRVPPHPSSERRAVY] of the GABABR1 subunit.
• Localization: Cell Membrane
• Specificity: GABA B receptor 1
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GABBR1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500 (ECL)
• Application Notes: By Western Blot a 108kDa band is predicted. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Theoretical MW: 116 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Control:

  Human Brain Whole Tissue Lysate (Adult Whole Normal)

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for GABA-B R1 Antibody - BSA Free

• FLJ92613
• GABA B R1
• GABABR1
• GABBR1
• GABBR1-3
• gamma-aminobutyric acid (GABA) B receptor, 1
• gamma-aminobutyric acid type B receptor subunit 1
• Gb1
• GPRC3A
• GPRC3Asubunit 1c
• hGB1a
• seven transmembrane helix receptor

Background

The inhibitory neurotransmitter, GABA, acts through two ligand-gated channels, GABA A and GABA C receptors and GABA B, the latter of which acts through a G protein mechanism. GABA BR1 is one of two G-protein coupled receptors for GABAb that acts as a heteromeric assembly with GABA BR2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for GABA-B R1 Antibody (NB300-160)(3)

Publications using NB300-160

• Luo C, Rajput AH, Robinson CA, Rajput A. Gamma-aminobutyric acid (GABA)-B receptor 1 in cerebellar cortex of essential tremor. J Clin Neurosci. 2012-02-07 [PMID: 22321358] (WB, Human)
• Fatemi SH, Folsom TD, Thuras PD. Deficits in GABA(B) receptor system in schizophrenia and mood disorders: a postmortem study Schizophr Res 2011-05-01 [PMID: 21303731] (WB, Human)
• Fatemi SH, Folsom TD, Reutiman TJ et al. Expression of GABA(B) receptors is altered in brains of subjects with autism. Cerebellum 2009-03-01 [PMID: 19002745] (WB, Human)

Bioinformatics

• Gene Symbol: GABBR1
• Entrez:
  • 2550(Human)
• Uniprot:
  • Q9UBS5(Human)