G3BP1 Antibody (23GB1725)

• Reactivity: Hu, Mu, Rt
• Applications: WB, Flow, ICC/IF
• Clone: 23GB1725
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

G3BP1 Antibody (23GB1725) Summary

• Immunogen: A synthesized peptide derived from human G3BP1 (Uniprot: Q13283)
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: G3BP1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for G3BP1 Antibody (23GB1725)

• ATP-dependent DNA helicase VIII
• EC 3.6.1
• EC 3.6.4.12
• EC 3.6.4.13
• G3BP-1
• G3BPRas-GTPase-activating protein SH3-domain-binding protein
• GAP binding protein
• GAP SH3 domain-binding protein 1
• GTPase activating protein (SH3 domain) binding protein 1
• hDH VIII
• HDH-VIII
• MGC111040
• ras GTPase-activating protein-binding protein 1
• RasGAP-associated endoribonuclease G3BP

Background

G3BP1 encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: G3BP1