G3BP1 Products

Description

G3BP1 encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Bioinformatics

Entrez	10146 Human 171092 Rat 27041 Mouse
Uniprot	AAH06997 Human NP_005745 Human NP_005745.1 Human NP_938405 Human Q13283 Human
Product By Gene ID	10146
Alternate Names	ATP-dependent DNA helicase VIII EC 3.6.1 EC 3.6.4.12 EC 3.6.4.13 G3BP-1 G3BPRas-GTPase-activating protein SH3-domain-binding protein GAP binding protein GAP SH3 domain-binding protein 1 GTPase activating protein (SH3 domain) binding protein 1 hDH VIII HDH-VIII MGC111040 ras GTPase-activating protein-binding protein 1 RasGAP-associated endoribonuclease G3BP

Research Areas for G3BP1

Find related products by research area and learn more about each of the different research areas below.

Core ESC-Like Genes
Phospho-Specific
Stem Cell Markers

Related G3BP1 Blog Posts

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Understanding ‘Y’ in Breast Cancer: Crucial Role of DNA/RNA-binding Protein YB-1 in the Development, Pre-Invasive, and Metastatic Phases Jamshed Arslan, Pharm D, PhD In the United States, 1 in 8 women will be diagnosed with breast cancer in her lifetime.1 Despite the prevalence, cancer genesis is a mystery. The heterogeneity of cancers makes it diff...    Read more.

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