FSHR Antibody (626717) [DyLight 350]

• Applications: Flow, B/N, CyTOF-ready
• Clone: 626717
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 350

FSHR Antibody (626717) [DyLight 350] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: NS0 mouse myeloma cell line transfected with human FSH R
  Accession # M65085
• Specificity: Detects human FSH R in direct ELISAs.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: FSHR
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Neutralization
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product MAB65591. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Reactivity Notes

0

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for FSHR Antibody (626717) [DyLight 350]

• follicle stimulating hormone receptor
• follicle-stimulating hormone receptor
• Follitropin receptor
• FSH R
• FSH receptor
• FSHR
• FSH-R
• LGR1
• LGR1FSHRO
• MGC141667
• MGC141668
• ODG1

Background

Follicle-stimulating hormone (FSH), also called follitropin, belongs to the family of glycoprotein hormones that also includes luteininizing hormone and thyroid-stimulating hormone. These hormones are secreted by the pituitary and exist as heterodimers, consisting of a common alpha subunit and a homologous but distinct beta subunit. While the alpha subunit of FSH is involved in the binding of FSH to the receptor, follicle-stimulating hormone receptor (FSHR), the beta subunit stabilizes this interaction. This heterodimer regulates a variety of processes, including secretion, post-translational modification and signal transduction. Both FSH and FSHR are localized to Sertoli cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FSHR