Frizzled-9 Antibody

Immunohistochemistry-Paraffin: Frizzled-9 Antibody [NB100-94906] - Staining of paraffin embedded Human Thyroid. Antibody at 5 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Immunohistochemistry-Paraffin: Frizzled-9 Antibody [NB100-94906] - Staining of paraffin embedded Human Testis. Antibody at 5 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

• Reactivity: Hu, Mu, Rt
• Applications: ELISA, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

Frizzled-9 Antibody Summary

• Description: Novus Biologicals Goat Frizzled-9 Antibody (NB100-94906) is a polyclonal antibody validated for use in IHC and ELISA. Anti-Frizzled-9 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence C-TKTDPSLENPTH corresponding to C-Terminus according to NP_003499.1.
• Epitope: C-TKTDPSLENPTH
• Predicted Species: Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: FZD9
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 5 ug/mL
  • Immunohistochemistry-Paraffin 5 ug/mL
  • Peptide ELISA Detection limit 1:32000

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Frizzled-9 Antibody

• CD349 antigen
• CD349
• frizzled (Drosophila) homolog 9
• frizzled homolog 9 (Drosophila)
• Frizzled9
• Frizzled-9
• fz-9
• FZD3fzE6
• FZD9
• FzE6
• hFz9

Background

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Frizzled-9 Antibody (NB100-94906)(1)

Publication using NB100-94906

• Winn RA, Van Scoyk M, Hammond M et al. Antitumorigenic effect of Wnt 7a and Fzd 9 in non-small cell lung cancer cells is mediated through ERK-5-dependent activation of peroxisome proliferator-activated receptor gamma. J Biol Chem 2006-09-15 [PMID: 16835228]

Bioinformatics

• Gene Symbol: FZD9
• Entrez:
  • 8326(Human)
  • 14371(Mouse)
  • 266608(Rat)
• Uniprot:
  • NP_003499.1(Human)