Frizzled-8 Antibody

Images

 
Immunohistochemistry-Paraffin: Frizzled-8 Antibody [NLS4776] - Anti-FZD8 / Frizzled 8 antibody IHC of human brain, substantia nigra. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced ...read more
Immunohistochemistry-Paraffin: Frizzled-8 Antibody [NLS4776] - IHC analysis of Pancreas, Islet of Langerhan's using this antibody at 7 ug/ ml.
Immunohistochemistry-Paraffin: Frizzled-8 Antibody [NLS4776] - Analysis of anti-FZD8 / Frizzled 8 antibody with human brain, amygdala.
Immunohistochemistry-Paraffin: Frizzled-8 Antibody [NLS4776] - Anti-FZD8 / Frizzled 8 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after ...read more
Immunohistochemistry-Paraffin: Frizzled-8 Antibody [NLS4776] - Anti-FZD8 / Frizzled 8 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, Eq, Mk, Pm, Xp, OpSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Frizzled-8 Antibody Summary

Immunogen
Synthetic 12 amino acid peptide from N-terminal extracellular domain of human FZD8 / Frizzled 8.
Specificity
Human FZD8 / Frizzled 8. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Opossum (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FZD8
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 7 - 17 ug/ml

Reactivity Notes

Marmoset. Predicted cross-reactivity based on sequence identity: Panda (100%), Lizard (83%), Seabass (83%), Pufferfish (83%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Frizzled-8 Antibody

  • frizzled (Drosophila) homolog 8
  • frizzled 8
  • frizzled family receptor 8
  • frizzled homolog 8 (Drosophila)
  • Frizzled8
  • Frizzled-8
  • FZ-8
  • FZD8
  • hFZ8

Background

Members of the Frizzled family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Frizzled 8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. Its expression has been reported in brain, heart, kidney, pancreas, and skeletal muscle. ESTs have been isolated from embryo, eye, head/neck, heart, kidney, liver/spleen, pancreas, prostate, and testis libraries, as well as many tumor libraries. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol FZD8
Entrez