Species: Mu
Applications: WB
Host: Rat Monoclonal
Species: Hu
Applications: WB, Flow
Host: Rabbit Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: AC
Description
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
|
| Product By Gene ID |
8325 |
| Alternate Names |
- frizzled (Drosophila) homolog 8
- frizzled 8
- frizzled family receptor 8
- frizzled homolog 8 (Drosophila)
- Frizzled8
- Frizzled-8
- FZ-8
- FZD8
- hFZ8
|
![Binding Activity Frizzled-8 [Biotin]](http://images.novusbio.com/fullsize2/Frizzled8_BT6129_2539.jpg)
![SDS-PAGE Frizzled-8 [Biotin]](http://images.novusbio.com/fullsize2/Frizzled8_BT6129_2452.jpg)