Frizzled-8 Products

Antibodies
Frizzled-8 Antibody
Frizzled-8 Antibody
NB100-2439
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
Frizzled-8 Antibody
Frizzled-8 Antibody
NBP1-87410
Species: Hu, Mu, Rt, Mouse, Rat
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Frizzled-8 Antibody
Frizzled-8 Antibody
AF112
Species: Mu
Applications: WB, IHC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Proteins
Frizzled-8 Partial Recombinan ...
Frizzled-8 Partial Recombinant Pro...
H00008325-Q01
Species: Hu
Applications: WB, ELISA, PA
Frizzled-8 Recombinant Protei ...
Frizzled-8 Recombinant Protein Ant...
NBP1-87410PEP
Species: Hu
Applications: AC
RNAi

Description

"Frizzled-8 is a receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Mouse
Product By Gene ID 8325
Alternate Names
  • frizzled family receptor 8
  • hFz8
  • frizzled 8
  • Fz-8
  • FZ-8
  • hFZ8
  • frizzled (Drosophila) homolog 8
  • frizzled-8
  • frizzled homolog 8 (Drosophila)

Research Areas for Frizzled-8

Find related products by research area and learn more about each of the different research areas below.

GPCR
Growth and Development
Neuronal Cell Markers
Signal Transduction
Wnt Signaling Pathway

PTMs for Frizzled-8

Learn more about PTMs related to Frizzled-8.

Phosphorylation
Glycosylation

Bioinformatics Tool for Frizzled-8

Discover related pathways, diseases and genes to Frizzled-8. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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