FNTA Antibody

ELISA: FNTA Antibody [21410002] - Affinity Purified

Product Discontinued

FNTA Antibody Summary

• Immunogen: This antibody is specific for the N Terminus Region of the target protein.
• Specificity: This product is specific for Human FNTA.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: FNTA
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:250-1:2000
  • Western Blot 1:5000-1:20000
• Application Notes: This antibody is useful in ELISA, Western Blot and Immunohistochemistry-Paraffin.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for FNTA Antibody

• CAAX farnesyltransferase subunit alpha
• EC 2.5.1.58
• EC 2.5.1.59
• farnesyl-protein transferase alpha-subunit
• farnesyltransferase, CAAX box, alpha
• FNTA
• FPTA
• FTase-alpha
• GGTase-I-alpha
• MGC99680
• PGGT1A
• protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
• protein prenyltransferase alpha subunit repeat containing 2
• PTAR2
• Ras proteins prenyltransferase subunit alpha
• type I protein geranyl-geranyltransferase alpha subunit
• Type I protein geranyl-geranyltransferase subunit alpha

Background

Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants encoding different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for FNTA Antibody (21410002)(2)

Publications using 21410002

• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.

Bioinformatics

• Gene Symbol: FNTA
• Uniprot:
  • NM_002027(Human)