FNTA Products

Description

Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants encoding different isoforms.

Bioinformatics

Entrez	2339 Human
Uniprot	A6NJW0 Human AAH17029 Human NM_002027 Human NP_002018 Human
Product By Gene ID	2339
Alternate Names	CAAX farnesyltransferase subunit alpha EC 2.5.1.58 EC 2.5.1.59 farnesyl-protein transferase alpha-subunit farnesyltransferase, CAAX box, alpha FPTA FTase-alpha GGTase-I-alpha MGC99680 PGGT1A protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha protein prenyltransferase alpha subunit repeat containing 2 PTAR2 Ras proteins prenyltransferase subunit alpha type I protein geranyl-geranyltransferase alpha subunit Type I protein geranyl-geranyltransferase subunit alpha

Research Areas for FNTA

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Signal Transduction