FMO3 Antibody (OTI3H1) [HRP]

• Reactivity: Hu
• Applications: WB, IHC
• Clone: OTI3H1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: HRP

FMO3 Antibody (OTI3H1) [HRP] Summary

• Immunogen: Recombinant protein fragment corresponding to amino acids 1-291 of human FMO3 (NP_008825) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: FMO3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for FMO3 Antibody (OTI3H1) [HRP]

• dimethylaniline monooxygenase [N-oxide-forming] 3
• Dimethylaniline oxidase 3
• dJ127D3.1
• EC 1.14.13.8
• flavin containing monooxygenase 3
• FMO 3
• FMO form 2
• FMO II
• FMOII
• Hepatic flavin-containing monooxygenase 3
• hepatic flavin-containing monooxygenase-3
• MGC34400
• TMAU

Background

The mammalian flavin-containing monooxygenases (FMO; EC 1.14.13.8) represent a multigene family whose gene products are localized in the endoplasmic reticulum of many tissues. These enzymes catalyze the NADPH-dependent oxidative metabolism of many drugs, pesticides, and other foreign compounds. Their substrates are soft nucleophiles with an electron-rich center, typically a nitrogen, sulfur or phosphorus-containing functional group, as the site for oxidative attack by the enzyme (Ziegler, 1990 [PubMed 2203193]; Hines et al., 1994 [PubMed 8128486]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FMO3