Ficolin-2 Antibody (19) - BSA Free

• Reactivity: Hu
• Applications: WB, ELISA, IP
• Clone: 19
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

Ficolin-2 Antibody (19) - BSA Free Summary

• Description: Novus Biologicals Mouse Ficolin-2 Antibody (19) - BSA Free (NBP1-05042) is a monoclonal antibody validated for use in WB, ELISA, ICC/IF and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Purified procaryot expressed recombinant human L-Ficolin and full-length L-Ficolin (Ficolin-2) protein.
• Specificity: Reacts specifically with L-Ficolin. No cross reactivity is seen with M-Ficolin (Ficolin-1) and H-Ficolin (Ficolin-3).
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: FCN2
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:4000
  • Immunoprecipitation 1:10-1:500
  • Western Blot 1:100-1:2000
• Application Notes: ELISA: NBP1-05042 is especially well suited as detecting antibody in a sandwich ELISA in combination with NBP2-21613. (1) Furthermore, in ELISA, NBP1-05042 reacts with recombinant L-Ficolin coated directly into the microtiter well.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 10mM Phosphate (pH 7.4) and 0.5M NaCl
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein A or G purified

Alternate Names for Ficolin-2 Antibody (19) - BSA Free

• 37 kDa elastin-binding protein
• Collagen/fibrinogen domain-containing protein 2
• EBP-37ficolin (collagen/fibrinogen domain-containing lectin) 2 (hucolin)
• FCN2
• FCNL
• FCNLficolin B
• ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)
• Ficolin2
• Ficolin-2
• ficolin-B
• ficolin-beta
• Hucolin
• L-Ficolin
• P35
• Serum lectin p35

Background

L-Ficolin (Ficolin-2) is an innate immunity pattern recognition molecule found in human serum. L-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP), such as carbohydrates (GlcNAc), lipoteichoic acid and acetylated groups thereby facilitating phagocytosis and activation of complement through the lectin route using the same serine proteases as mannose-binding lectin (MBL) named MASP ((MBL)-associated serine protease) (1).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FCN2