Ficolin-2 Antibody (19) [FITC]

• Reactivity: Hu
• Applications: WB, ELISA, IP
• Clone: 19
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: FITC

Ficolin-2 Antibody (19) [FITC] Summary

• Immunogen: Purified procaryot expressed recombinant human L-Ficolin and full-length L-Ficolin (Ficolin-2) protein.
• Specificity: Reacts specifically with L-Ficolin. No cross reactivity is seen with M-Ficolin (Ficolin-1) and H-Ficolin (Ficolin-3).
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: FCN2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Alternate Names for Ficolin-2 Antibody (19) [FITC]

• 37 kDa elastin-binding protein
• Collagen/fibrinogen domain-containing protein 2
• EBP-37ficolin (collagen/fibrinogen domain-containing lectin) 2 (hucolin)
• FCN2
• FCNL
• FCNLficolin B
• ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)
• Ficolin2
• Ficolin-2
• ficolin-B
• ficolin-beta
• Hucolin
• L-Ficolin
• P35
• Serum lectin p35

Background

The product of this gene belongs to the ficolin family of proteins. This family is characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. This gene is predominantly expressed in the liver, and has been shown to have carbohydrate binding and opsonic activities. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Ficolin-2 Antibody (NBP1-05042F)(1)

Publication using NBP1-05042F

• Macarie RD, Tucureanu MM, Ciortan L et al. Ficolin-2 amplifies inflammation in macrophage-smooth muscle cell cross-talk and increases monocyte transmigration by mechanisms involving IL-1? and IL-6 Scientific reports 2023-11-08 [PMID: 37940674] (ICC/IF, Human)

Bioinformatics

• Gene Symbol: FCN2