Fgr Antibody (6G2)

Images

 
Western Blot: Fgr Antibody (6G2) [NBP1-47536] - Western blot analysis using anti-FGR mAb against HL60 (1) Raw264.7 (2) cell lysate.
Immunohistochemistry-Paraffin: Fgr Antibody (6G2) [NBP1-47536] - Immunohistochemical analysis of paraffin-embedded human Spleen tissues using FGR mouse mAb

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, IHC-P
Clone
6G2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Fgr Antibody (6G2) Summary

Immunogen
Purified recombinant fragment of human FGR expressed in E. Coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
FGR
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1: 500-1:2000
  • ELISA 1:10000
  • Immunohistochemistry-Paraffin
Theoretical MW
56 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human,Mouse. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Ascites
Preservative
0.03% Sodium Azide
Purity
Unpurified

Alternate Names for Fgr Antibody (6G2)

  • c-fgr
  • c-src-2 proto-oncogene
  • c-src2
  • EC 2.7.10
  • EC 2.7.10.2
  • Fgr
  • FLJ43153
  • Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
  • MGC75096
  • p55-c-fgr protein
  • p55c-fgr
  • p55-Fgr
  • p58c-fgr
  • Proto-oncogene c-Fgr
  • proto-oncogene tyrosine-protein kinase FGR
  • Src2
  • SRC2c-fgr protooncogene
  • tyrosine-protein kinase Fgr

Background

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FGR
Entrez