FERMT3/URP2 Antibody

Western Blot: URP2 Antibody [NBP2-20821] - Sample (30 ug of whole cell lysate) A: Jurkat B: Raji 7. 5% SDS PAGE gel, diluted at 1:1000.

Immunocytochemistry/Immunofluorescence: FERMT3/URP2 Antibody [NBP2-20821] - URP2 antibody detects URP2 protein at cytoplasm by immunofluorescent analysis.Sample: Jurkat cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: URP2 protein stained by URP2 antibody diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 um.

Immunohistochemistry-Paraffin: URP2 Antibody [NBP2-20821] - Immunohistochemical analysis of paraffin-embedded RT2 xenograft, using antibody at 1:500 dilution.

Immunohistochemistry-Paraffin: URP2 Antibody [NBP2-20821] - Immunohistochemical analysis of paraffin-embedded Gastric ca, using antibody at 1:500 dilution.

• Reactivity: Hu, Rt
• Applications: WB, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

FERMT3/URP2 Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human FERMT3/URP2. The exact sequence is proprietary.
• Localization: Cytoplasm (Probable); Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: FERMT3
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 76 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS, 1% BSA, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for FERMT3/URP2 Antibody

• fermitin family member 3
• FERMT3
• KIND3
• KIND3fermitin family homolog 3 (Drosophila)
• Kindlin 3
• Kindlin-3
• MGC10966
• MIG-2
• MIG2B
• MIG2BURP2SF
• MIG2-like protein
• UNC-112 related protein 2
• UNC112C
• Unc-112-related protein 2
• URP2
• URP2fermitin family homolog 3
• URP2SF

Background

Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: FERMT3
• Uniprot:
  • Q86UX7(Human)