FEN-1 Antibody

Product Discontinued

FEN-1 Antibody Summary

• Immunogen: Recombinant full-length human FEN-1 protein
• Localization: Nuclear
• Specificity: This is specific for FEN-1.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: FEN1
• Purity: Whole Antiserum

Applications/Dilutions

• Dilutions:
  • Western Blot 1:2500
• Control:

  NIH 3T3 Whole Cell Lysate
  FEN-1 Overexpression Lysate
  HeLa Whole Cell Lysate

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Whole Antiserum

Alternate Names for FEN-1 Antibody

• EC 3.1
• FEN1
• FEN-1
• FEN-1hFEN-1
• flap structure-specific endonuclease 1DNase IV
• Maturation factor 1
• maturation factor-1
• MF1flap endonuclease 1
• RAD2

Background

FEN-1 (Flap EndoNuclease and Five prime Exonuclease) is a 42kDa protein that functions as an endonuclease and cleaves branched DNA structures containing single-stranded 5' flaps or as an exonuclease on DNA nicks and gaps. FEN-1 endonuclease and exonuclease activities are stimulated by an association with proliferating cell nuclear antigen (PCNA) in the nucleus. FEN-1 is believed to have important roles in DNA replication and repair, and is required in cell-free DNA replication systems.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FEN1
• Entrez:
  • 2237(Human)
  • 14156(Mouse)