FE65 Peptide

Product Discontinued

FE65 Peptide Summary

• Immunogen: This protein is not active and should not be used for experiments requiring activity.
• Protein/Peptide Type: Peptide
• Gene: APBB1

Applications/Dilutions

• Dilutions:
  • Block/Neutralize
• Application Notes: This peptide is useful as a blocking peptide for PAB4704.
  This product may contain endotoxins and is not suitable for use with live cells.
  
  For further blocking peptide related protocol, click here.

Reactivity Notes

Human

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized with 100% acetonitrile. Reconstitute with 100 uL deionized water for a final concentration of 1 mg/mL.
• Preservative: No Preservative

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for FE65 Peptide

• adaptor protein FE65a2
• amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
• amyloid beta A4 precursor protein-binding, family B, member 1
• Fe65
• FE65amyloid beta A4 precursor protein-binding family B member 1
• MGC:9072
• Protein Fe65
• RIR
• stat-like protein

Background

Amyloid beta A4 precursor protein-binding family B member 1, also known as FE65, is a signaling adaptor of APP protein. The FE65/APP complex has been shown to translocate into the cell nucleus and regulate gene expression, indicating that FE65 may be critical in the pathogenesis of Alzheimer's disease. Genetic studies in mice validated FE65-APP interaction and molecular studies provided evidence on the role of the complex in abnormal signaling detected in brains of Alzheimer's Disease patients.

FE65 antibodies are useful tools for research on Alzheimer's disease progression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: APBB1