CD82/Kai-1 Antibody (C33) Summary
C91/PL (human HTLV-1+ T cell line).
The antibody C33 reacts with CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.
Protein A purified
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- Western Blot 1:500-1:2000
- Flow Cytometry 1:50-1:250
- Immunocytochemistry/Immunofluorescence 1:50-1:300
- Immunohistochemistry 1:50-1:300
- Immunohistochemistry-Paraffin 1:50-1:300
- Immunoprecipitation 1:10-1:500
In human MOLT-4 T-cell line the antibody C33 inhibits syncytium formation induced by coculture with human T-cell leukemia virus type 1 (HTLV-1)-positive human T-cell lines.
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
PBS (pH 7.4)
15mM Sodium Azide
Protein A purified
Alternate Names for CD82/Kai-1 Antibody (C33)
- CD82 antigenC33
- CD82 molecule
- IA4C33 antigen
- Inducible membrane protein R2
- kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyteantigen, antigen detected by monoclonal and IA4))
- Metastasis suppressor Kangai-1
- Suppressor of tumorigenicity 6 protein
CD82 (KAI1), a member of the tetraspanin family, forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules. These complexes influence adhesion, morphology, activation, proliferation and differentiation of B, T and other cells. CD82 regulates cytoskeleton rearrangement and may participate in the turnover of the tetraspanin complex members. Besides in the plasma membrane, CD82 is localized also in endosome/lysosome compartments. Tumour-suppressive roles of CD82 have been demonstrated.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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