Fc gamma RIIB/CD32b Antibody (190907) [Alexa Fluor® 594]

• Reactivity: Mu
• Applications: WB, ELISA(Cap), ELISA(Det)
• Clone: 190907
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 594

Fc gamma RIIB/CD32b Antibody (190907) [Alexa Fluor® 594] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Fcγ RIIB
  aa 40-217
  Accession # P08101
• Specificity: Detects mouse Fc gamma RIIB in direct ELISAs. In direct ELISAs, this antibody shows 100% cross-reactivity with recombinant mouse (rm) Fc gamma RIII. In ELISAs, this antibody shows approximately 7% cross-reactivity with rmFc gamma RIII.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA Capture (Matched Antibody Pair)
  • ELISA Detection (Matched Antibody Pair)
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Fc gamma RIIB/CD32b Antibody (190907) [Alexa Fluor® 594]

• CD32 antigen
• CD32b
• CD32Fc fragment of IgG, low affinity II, receptor for (CD32)
• CDw32
• Fc fragment of IgG, low affinity IIb, receptor (CD32)
• Fc fragment of IgG, low affinity IIb, receptor for (CD32)
• Fc gamma RIIB
• FCG2
• Fc-gamma RII-b
• fc-gamma-RIIb
• FCGR2
• FCGR2B
• FcgRIIB
• FCRIIB
• fcRII-b
• IGFR2
• IgG Fc receptor II-b
• low affinity immunoglobulin gamma Fc region receptor II-b

Background

Fc gamma RIIB, also known as CD32b, is a low affinity inhibitory receptor for the Fc portion of the IgG molecules. Fc gamma RIIB is expressed on B cells, macrophages, neutrophils, and mast cells and is involved in phagocytosis of immune complexes and modulation of antibody production by B cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.