Fas/TNFRSF6/CD95 Antibody (4F8D6)

Images

 
Western Blot: Fas/TNFRSF6/CD95 Antibody (4F8D6) [NBP2-13078] - Figure 3: Western blot analysis using FAS mouse mAb against Hela (1), Jurkat (2) cell lysate.
Flow Cytometry: Fas/TNFRSF6/CD95 Antibody (4F8D6) [NBP2-13078] - Figure 4: Flow cytometric analysis of Hela cells using FAS mouse mAb (green) and negative control (red).
Western Blot: Fas/TNFRSF6/CD95 Antibody (4F8D6) [NBP2-13078] - Figure 2: Western blot analysis using FAS mAb against human FAS (AA: 87-278) recombinant protein. (Expected MW is 47.2 kDa)
ELISA: Fas/TNFRSF6/CD95 Antibody (4F8D6) [NBP2-13078] - Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, CyTOF-ready
Clone
4F8D6
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
37.7 mg/ml

Fas/TNFRSF6/CD95 Antibody (4F8D6) Summary

Immunogen
Purified recombinant fragment of human FAS expressed in E. Coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
FAS
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:2000
  • ELISA 1:10000
  • Flow Cytometry 1:200-1:400
  • CyTOF-ready
Theoretical MW
37.7 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publications using NBP2-13078.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Concentration
37.7 mg/ml
Purity
Protein A or G purified

Alternate Names for Fas/TNFRSF6/CD95 Antibody (4F8D6)

  • Apo-1 antigen
  • Apo-1
  • apoptosis antigen 1
  • Apoptosis-mediating surface antigen FAS
  • APT1
  • APT1FASTM
  • CD95 antigen
  • CD95
  • CD95ALPS1A
  • Fas (TNF receptor superfamily, member 6)
  • Fas AMA
  • Fas antigen
  • Fas
  • FAS1
  • FASLG receptor
  • TNFRSF6
  • TNFRSF6member 6
  • tumor necrosis factor receptor superfamily member 6

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB,

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Fas/TNFRSF6/CD95 Antibody (NBP2-13078)(2)

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Bioinformatics

Gene Symbol FAS
Entrez