FAM3D Antibody (358203)

• Reactivity: Hu
• Applications: WB
• Clone: 358203
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: LYOPH

FAM3D Antibody (358203) Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human FAM3D
  Trp39-Phe224
  Accession # Q96BQ1
• Specificity: Detects human FAM3D in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) FAM3A, rhFAM3B, rhFAM3C, or recombinant mouse FAM3D is observed.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: FAM3D
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FAM3D Antibody (358203)

• cytokine-like protein EF-7
• EF7
• FAM3D
• family with sequence similarity 3, member D
• OIT1

Background

Family with sequence similarity 3, member D (FAM3D), also known as EF-7, belongs to the novel cytokine-like family whose members are secreted four-helix bundle proteins. Human FAM3D is abundantly expressed in placenta as a 224 amino acid (aa) residue precursor with a 25 aa signal sequence. The aa sequence of mature human FAM3D is 74% identical to that of mouse FAM3D.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for FAM3D Antibody (MAB2869)(3)

Publications using MAB2869

• Yicong Shen, Zhigang Dong, Fangfang Fan, Kaiyin Li, Shirong Zhu, Rongbo Dai et al. Targeting cytokine-like protein FAM3D lowers blood pressure in hypertension Cell Reports Medicine 2023-06-20 [PMID: 37301198]
• Li He, Yi Fu, Jingna Deng, Yicong Shen, Yingbao Wang, Fang Yu et al. Deficiency of FAM3D (Family With Sequence Similarity 3, Member D), A Novel Chemokine, Attenuates Neutrophil Recruitment and Ameliorates Abdominal Aortic Aneurysm Development Arteriosclerosis, Thrombosis, and Vascular Biology 2018-07-01 [PMID: 29853563]
• Li He, Yi Fu, Jingna Deng, Yicong Shen, Yingbao Wang, Fang Yu et al. Deficiency of FAM3D (Family With Sequence Similarity 3, Member D), A Novel Chemokine, Attenuates Neutrophil Recruitment and Ameliorates Abdominal Aortic Aneurysm Development Arteriosclerosis, Thrombosis, and Vascular Biology 2018-07-01 [PMID: 29853563] (Immunohistochemistry, Mouse)

Bioinformatics

• Gene Symbol: FAM3D
• Uniprot:
  • Q96BQ1()