FAM3B Antibody [Alexa Fluor® 405]

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 405

FAM3B Antibody [Alexa Fluor® 405] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse FAM3B
  Glu30-Arg235
  Accession # Q9D309
• Specificity: Detects mouse FAM3B in direct ELISAs and Western blots. In direct ELISAs, approximately 35% cross‑reactivity with recombinant human FAM3B is observed, approximately 5% cross-reactivity with recombinant mouse (rm) FAM3C is observed, and
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FAM3B Antibody [Alexa Fluor® 405]

• 2-21
• C21orf11
• C21orf76PANDER
• chromosome 21 open reading frame 11
• Cytokine-like protein 2-21
• D21M16SJHU19e
• FAM3B
• family with sequence similarity 3, member B
• ORF9
• pancreatic derived factor
• Pancreatic-derived factor
• PANDER
• PRED44

Background

FAM3B, also known as Pancreatic-Derived factor (PANDER), is a secreted, monomeric, 23 kDa glycoprotein that belongs to a new family of four-helix bundle cytokines. It is highly expressed in pancreatic islet cells and reproductive epithelium. FAM3B has been shown to induce b-cell apoptosis and decrease insulin secretion. Two alternative N-termini, at Glu 30 and Ser 46, have been observed for mature FAM3B. The long version of mature mouse FAM3B shares 80%, 92%, and 75% amino acid sequence homology with the human, rat and canine mature FAM3B, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.